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by pszczola on Październik 8, 2018

There was no evidence of tumorigenicity when clopidogrel was administered for 78 weeks to mice and 104 weeks to rats at dosages up to 77 mg kg per day, which afforded plasma exposures 25 times that in humans at the recommended daily dose of 75 mg.

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Otherabnormal tastechillsweight lossincreased risk of bacterial and viral infectionlupuslike syndromeanaphylaxis.

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Inhibits peripheral lipolysisresulting in decreased triglyceride levelsAlso inhibits synthesis and increases clearance of very-low-density lipoproteins.

LovastatinMevacorpravastatinPravacholsimvastatinZocorfluvastatinLescolrosuvastatinCrestorand atorvastatinLipitorAll these increase the risk of a condition called rhabdomyolysismuscle injurythat when severe can lead to kidney damage and even deathRhabdomyolysis may occur as early as three weeks or several months after starting combination therapyThe benefit of combining gemfibrozil with statins does not outweigh the risk of rhabdomyolysis.

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